IKZF3 Polyclonal Antibody

IKZF3 Polyclonal Antibody

The IKZF3 polyclonal antibody is a highly specific and sensitive tool for the detection and quantification of IKZF3 protein expression in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human IKZF3 protein. The resulting polyclonal antibody is purified using a combination of protein A and protein G affinity chromatography to ensure high purity and specificity.

The IKZF3 protein, also known as AIOLOS, is a member of the Ikaros family of transcription factors that play critical roles in the regulation of lymphocyte development and differentiation. Dysregulation of IKZF3 expression has been implicated in various diseases, including autoimmune disorders and cancer. Therefore, the IKZF3 polyclonal antibody is an essential tool for researchers studying the molecular mechanisms underlying these diseases.

The IKZF3 polyclonal antibody has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. This antibody has been shown to specifically recognize IKZF3 protein in various human and mouse tissues, including lymphoid tissues, bone marrow, and spleen. Additionally, this antibody has been shown to detect endogenous IKZF3 protein expression in various cell lines, including Jurkat and Raji cells.

In summary, the IKZF3 polyclonal antibody is a highly specific and sensitive tool for the detection and quantification of IKZF3 protein expression in various biological samples. This antibody is an essential tool for researchers studying the molecular mechanisms underlying autoimmune disorders and cancer.