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KCNA5 Polyclonal Antibody
KCNA5 Polyclonal Antibody
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KCNA5 Polyclonal Antibody
The KCNA5 polyclonal antibody is a highly specific and sensitive tool for the detection and quantification of KCNA5 protein expression in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of the human KCNA5 protein. The resulting polyclonal antibody is purified using a combination of protein A and protein G affinity chromatography to ensure high purity and specificity.
KCNA5, also known as Kv1.5, is a voltage-gated potassium channel that plays a critical role in regulating the electrical activity of cardiac myocytes. Dysregulation of KCNA5 expression or function has been implicated in various cardiovascular diseases, including atrial fibrillation, ventricular arrhythmias, and heart failure. Therefore, accurate measurement of KCNA5 protein levels is essential for understanding the pathophysiology of these diseases and developing effective therapeutic strategies.
The KCNA5 polyclonal antibody has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits high sensitivity and specificity, with minimal cross-reactivity with other potassium channels or proteins. This antibody is suitable for use in both research and clinical settings, and it has been used in numerous studies to investigate the role of KCNA5 in cardiovascular disease.
In summary, the KCNA5 polyclonal antibody is a reliable and effective tool for the detection and quantification of KCNA5 protein expression. Its high specificity and sensitivity make it an ideal choice for researchers and clinicians studying the role of KCNA5 in cardiovascular disease.
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