IL17C Polyclonal Antibody

IL17C Polyclonal Antibody

The IL17C polyclonal antibody is a highly specific and sensitive tool for the detection and quantification of interleukin-17C (IL17C) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human IL17C protein. The resulting polyclonal antibody recognizes both the native and recombinant forms of IL17C with high affinity and specificity.

IL17C is a member of the interleukin-17 family of cytokines, which play a crucial role in the regulation of immune responses and inflammation. IL17C is primarily produced by epithelial cells and acts on various immune cells, including T cells, B cells, and neutrophils, to promote inflammation and host defense against pathogens. Dysregulation of IL17C signaling has been implicated in the pathogenesis of various inflammatory and autoimmune diseases, such as psoriasis, rheumatoid arthritis, and inflammatory bowel disease.

The IL17C polyclonal antibody can be used in a variety of applications, including Western blotting, ELISA, immunohistochemistry, and flow cytometry. It has been validated for use in human, mouse, and rat samples and exhibits minimal cross-reactivity with other interleukin-17 family members. This antibody is supplied as a purified IgG fraction and can be used at a recommended dilution of 1:1000 for Western blotting and 1:200 for immunohistochemistry.

In summary, the IL17C polyclonal antibody is a reliable and versatile tool for the detection and quantification of IL17C in various biological samples. Its high specificity and sensitivity make it an ideal choice for researchers studying the role of IL17C in immune responses and inflammation.