Human IL-1ra/IL-1F3(Interleukin 1 Receptor Antagonist) ELISA Kit

The HUMAN IL-1RA/IL-1F3 ELISA KIT is a highly sensitive and specific assay designed to measure the levels of Interleukin 1 Receptor Antagonist (IL-1RA) and Interleukin 1 Family Member 3 (IL-1F3) in human serum, plasma, and cell culture supernatants. The kit is based on the sandwich enzyme-linked immunosorbent assay (ELISA) principle, which utilizes two specific antibodies that recognize different epitopes of the target proteins. The assay has a detection range of 15.6-1000 pg/mL for IL-1RA and 31.2-2000 pg/mL for IL-1F3, with a sensitivity of 7.8 pg/mL and 15.6 pg/mL, respectively.

IL-1RA is a natural antagonist of the pro-inflammatory cytokine Interleukin 1 (IL-1), which plays a crucial role in the pathogenesis of various inflammatory diseases. Elevated levels of IL-1RA have been associated with a reduced risk of developing inflammatory disorders, such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease. On the other hand, IL-1F3 is a member of the IL-1 family that has been implicated in the regulation of innate immunity and inflammation. It has been shown to induce the production of pro-inflammatory cytokines and chemokines, suggesting a potential role in the pathogenesis of inflammatory diseases.

The HUMAN IL-1RA/IL-1F3 ELISA KIT provides a reliable and accurate tool for the quantitative measurement of IL-1RA and IL-1F3 in human biological samples. The kit includes all the necessary reagents and controls for the assay, and the protocol is simple and easy to follow. The results obtained from the assay can be used to monitor the levels of these cytokines in various clinical and research settings, and to investigate their potential roles in the pathogenesis of inflammatory diseases.