Human PAH(Phenylalanine Hydroxylase) ELISA Kit

The Human PAH (Phenylalanine Hydroxylase) ELISA Kit is a highly sensitive and specific assay designed for the quantitative measurement of PAH in human serum, plasma, and other biological fluids. This kit is based on the sandwich enzyme-linked immunosorbent assay (ELISA) principle, which utilizes two specific antibodies that recognize different epitopes of the target protein. The assay is easy to perform, with a simple and fast protocol that requires only a small amount of sample.

The PAH enzyme is responsible for the conversion of phenylalanine to tyrosine, a crucial step in the metabolism of this essential amino acid. Deficiency or dysfunction of PAH can lead to a rare genetic disorder called phenylketonuria (PKU), which results in the accumulation of toxic levels of phenylalanine in the body. Early diagnosis and treatment of PKU are critical to prevent severe neurological and developmental complications. The Human PAH ELISA Kit provides a reliable and accurate tool for the detection and monitoring of PAH levels in patients with PKU and other related disorders.

The Human PAH ELISA Kit has a wide dynamic range of detection, from 0.156 ng/mL to 10 ng/mL, with a sensitivity of 0.078 ng/mL. The kit includes all necessary reagents and controls, including a standard curve, positive and negative controls, and a sample diluent. The assay can be performed in a 96-well microplate format, with results obtained in less than 3 hours. The kit is suitable for research and clinical applications, and has been validated for use with human samples.