Human LAG3(Lymphocyte Activation Gene 3) ELISA Kit

The HUMAN LAG3 (LYMPHOCYTE ACTIVATION GENE 3) ELISA KIT is a highly sensitive and specific assay designed to detect and quantify the levels of LAG3 protein in human serum, plasma, and cell culture supernatants. LAG3 is a cell surface protein that plays a critical role in regulating immune responses by inhibiting T cell activation and proliferation. Dysregulation of LAG3 expression has been implicated in various autoimmune diseases and cancer, making it an important target for therapeutic intervention.

The ELISA kit utilizes a sandwich enzyme-linked immunosorbent assay format, where a capture antibody specific to LAG3 is coated onto a microplate. Samples are added to the wells, and any LAG3 present in the sample binds to the capture antibody. A detection antibody labeled with horseradish peroxidase is then added, which binds to the captured LAG3. The addition of a substrate solution causes a color change, which is proportional to the amount of LAG3 present in the sample. The assay has a detection range of 0.156-10 ng/mL, with a sensitivity of 0.078 ng/mL.

The HUMAN LAG3 ELISA KIT is a valuable tool for researchers studying the role of LAG3 in immune regulation and disease pathogenesis. It provides a reliable and reproducible method for quantifying LAG3 protein levels in various sample types, allowing for the identification of potential biomarkers and therapeutic targets. The kit is easy to use and can be completed in less than 4 hours, making it a convenient option for high-throughput screening. Overall, the HUMAN LAG3 ELISA KIT is a powerful tool for advancing our understanding of immune regulation and disease mechanisms.