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Elabscience

SKU:PKSH033282

Recombinant Human LAG3/CD223 Protein (His Tag)(Active)

Recombinant Human LAG3/CD223 Protein (His Tag)(Active)

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The Recombinant Human LAG3/CD223 Protein (HIS TAG)(ACTIVE) is a highly purified and biologically active protein that is produced using recombinant DNA technology. This protein is a member of the immunoglobulin superfamily and is also known as Lymphocyte Activation Gene 3 (LAG3) or CD223. It is a transmembrane protein that is expressed on the surface of activated T cells, regulatory T cells, and natural killer cells.

The Recombinant Human LAG3/CD223 Protein (HIS TAG)(ACTIVE) is produced in a mammalian expression system and is purified using a combination of chromatography techniques. The protein is then tagged with a histidine (HIS) tag to facilitate purification and detection. The protein is highly pure and has a molecular weight of approximately 70 kDa.

The Recombinant Human LAG3/CD223 Protein (HIS TAG)(ACTIVE) is a potent immune checkpoint inhibitor that has been shown to enhance T cell activation and proliferation. It binds to MHC class II molecules on antigen-presenting cells and inhibits T cell activation by downregulating the T cell receptor signaling pathway. This protein has been extensively studied in preclinical models and has shown promising results in the treatment of various cancers.

The Recombinant Human LAG3/CD223 Protein (HIS TAG)(ACTIVE) is supplied as a lyophilized powder and should be reconstituted in sterile water to a concentration of 0.1-1.0 mg/ml. It should be stored at -20°C or below and should not be subjected to repeated freeze-thaw cycles. This protein is intended for research use only and should not be used for diagnostic or therapeutic purposes.
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