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Elabscience

SKU:PKSV030379

Recombinant SARS-CoV-2 Spike RBD (K417T, E484K, N501Y)(rFc Tag)

Recombinant SARS-CoV-2 Spike RBD (K417T, E484K, N501Y)(rFc Tag)

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Introducing the Recombinant SARS-CoV-2 Spike RBD (K417T, E484K, N501Y)(rFc Tag), a cutting-edge product designed to facilitate advanced research and development in the field of virology. This meticulously engineered recombinant protein offers a comprehensive solution for studying the Spike Receptor Binding Domain (RBD) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with specific mutations, namely K417T, E484K, and N501Y, accompanied by an rFc tag for enhanced detection and analysis.

Crafted with utmost precision, this product serves as an invaluable tool for investigating the intricate interactions between the SARS-CoV-2 Spike protein and its receptor, angiotensin-converting enzyme 2 (ACE2). The inclusion of the K417T, E484K, and N501Y mutations allows researchers to delve deeper into the potential implications of these specific genetic alterations on viral infectivity, transmissibility, and immune evasion.

The rFc tag, a fusion protein consisting of the receptor-binding fragment (RBD) and the Fc region of human immunoglobulin G (IgG), empowers scientists with the ability to conveniently detect and purify the recombinant protein. This tag not only facilitates efficient protein purification but also enables facile quantification and characterization, thereby streamlining experimental workflows and ensuring accurate results.

The Recombinant SARS-CoV-2 Spike RBD (K417T, E484K, N501Y)(rFc Tag) is manufactured under stringent quality control measures, ensuring exceptional purity, stability, and bioactivity. Each batch undergoes rigorous testing to guarantee its conformity to the highest industry standards, providing researchers with reliable and reproducible results.

This product finds its applications in a wide range of scientific endeavors, including but not limited to vaccine development, antiviral drug screening, neutralizing antibody studies, and structural biology investigations. Its versatility and reliability make it an indispensable asset for laboratories, academic institutions, and pharmaceutical companies at the forefront of combating the ongoing global pandemic.

In summary, the Recombinant SARS-CoV-2 Spike RBD (K417T, E484K, N501Y)(rFc Tag) represents a state-of-the-art research tool, meticulously designed to facilitate comprehensive investigations into the SARS-CoV-2 Spike protein and its receptor interactions. With its specific mutations and rFc tag, this product empowers scientists with enhanced detection, purification, and analysis
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