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SKU:E-CK-A213-50 Assays
Annexin V-AF647/PI Apoptosis Kit
Annexin V-AF647/PI Apoptosis Kit
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$150.00 USD
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The Annexin V-AF647/PI Apoptosis Kit is a meticulously designed and scientifically advanced product that offers a comprehensive solution for the detection and quantification of apoptotic cells. This kit is specifically engineered to provide accurate and reliable results, making it an indispensable tool for researchers and scientists in the field of cell biology and apoptosis studies.
Featuring Annexin V conjugated with AF647 and Propidium Iodide (PI), this kit enables the discrimination of apoptotic cells from necrotic and healthy cells with exceptional precision. Annexin V, a calcium-dependent phospholipid-binding protein, has a high affinity for phosphatidylserine (PS), which is exposed on the outer leaflet of the plasma membrane during early stages of apoptosis. By utilizing the fluorescent properties of AF647, Annexin V-AF647 allows for the visualization and identification of apoptotic cells with remarkable sensitivity.
Furthermore, the inclusion of Propidium Iodide in this kit facilitates the differentiation between apoptotic and necrotic cells. PI is a membrane-impermeable dye that selectively stains the DNA of cells with compromised plasma membranes, such as necrotic cells. By combining Annexin V-AF647 and PI, this kit enables the simultaneous detection of early apoptotic (Annexin V+/PI-), late apoptotic (Annexin V+/PI+), necrotic (Annexin V-/PI+), and viable (Annexin V-/PI-) cells, providing a comprehensive analysis of cellular apoptosis.
The Annexin V-AF647/PI Apoptosis Kit is not only highly sensitive and accurate but also user-friendly. With its straightforward protocol and optimized reagents, it ensures ease of use and reproducibility, saving valuable time and resources in the laboratory. Additionally, this kit is compatible with various sample types, including cultured cells and tissue sections, allowing for versatile applications in diverse research settings.
In summary, the Annexin V-AF647/PI Apoptosis Kit is an indispensable tool for researchers and scientists seeking to unravel the intricate mechanisms of apoptosis. With its exceptional sensitivity, accuracy, and user-friendly design, this kit empowers researchers to obtain reliable and comprehensive data, advancing our understanding of cellular processes and contributing to breakthrough discoveries in the field of cell biology.
Featuring Annexin V conjugated with AF647 and Propidium Iodide (PI), this kit enables the discrimination of apoptotic cells from necrotic and healthy cells with exceptional precision. Annexin V, a calcium-dependent phospholipid-binding protein, has a high affinity for phosphatidylserine (PS), which is exposed on the outer leaflet of the plasma membrane during early stages of apoptosis. By utilizing the fluorescent properties of AF647, Annexin V-AF647 allows for the visualization and identification of apoptotic cells with remarkable sensitivity.
Furthermore, the inclusion of Propidium Iodide in this kit facilitates the differentiation between apoptotic and necrotic cells. PI is a membrane-impermeable dye that selectively stains the DNA of cells with compromised plasma membranes, such as necrotic cells. By combining Annexin V-AF647 and PI, this kit enables the simultaneous detection of early apoptotic (Annexin V+/PI-), late apoptotic (Annexin V+/PI+), necrotic (Annexin V-/PI+), and viable (Annexin V-/PI-) cells, providing a comprehensive analysis of cellular apoptosis.
The Annexin V-AF647/PI Apoptosis Kit is not only highly sensitive and accurate but also user-friendly. With its straightforward protocol and optimized reagents, it ensures ease of use and reproducibility, saving valuable time and resources in the laboratory. Additionally, this kit is compatible with various sample types, including cultured cells and tissue sections, allowing for versatile applications in diverse research settings.
In summary, the Annexin V-AF647/PI Apoptosis Kit is an indispensable tool for researchers and scientists seeking to unravel the intricate mechanisms of apoptosis. With its exceptional sensitivity, accuracy, and user-friendly design, this kit empowers researchers to obtain reliable and comprehensive data, advancing our understanding of cellular processes and contributing to breakthrough discoveries in the field of cell biology.
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