APC Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]

The APC ANTI-MOUSE CD274/PD-L1 ANTIBODY[10F.9G2] is a highly specific and sensitive monoclonal antibody that is designed to detect and quantify the expression of CD274/PD-L1 in mouse samples. This antibody is conjugated with APC, which is a fluorescent dye that emits a red signal upon excitation with a laser. This allows for easy detection and analysis of CD274/PD-L1 expression in flow cytometry and other fluorescence-based assays.

The CD274/PD-L1 protein is a key immune checkpoint molecule that plays a critical role in regulating the immune response. It is expressed on the surface of various cells, including tumor cells, and interacts with its receptor PD-1 on T cells to inhibit their activation and proliferation. This interaction is exploited by cancer cells to evade immune surveillance and promote tumor growth. Therefore, targeting CD274/PD-L1 with antibodies has emerged as a promising strategy for cancer immunotherapy.

The APC ANTI-MOUSE CD274/PD-L1 ANTIBODY[10F.9G2] has been extensively validated for its specificity and sensitivity in detecting CD274/PD-L1 expression in mouse tissues and cell lines. It has been shown to recognize a unique epitope on CD274/PD-L1 and does not cross-react with other related proteins. Moreover, it exhibits minimal background staining and high signal-to-noise ratio, making it an ideal tool for studying the role of CD274/PD-L1 in cancer and other diseases.