PE Anti-Mouse MHC II (I-A/I-E) Antibody[M5/114]

The PE Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114] is a highly specific monoclonal antibody that is designed to recognize and bind to the major histocompatibility complex (MHC) class II molecules in mice. This antibody is conjugated with phycoerythrin (PE), which is a fluorescent protein that allows for easy detection and visualization of the target molecule. The M5/114 antibody is widely used in research applications such as flow cytometry, immunohistochemistry, and western blotting.

The MHC class II molecules are expressed on the surface of antigen-presenting cells (APCs) such as dendritic cells, macrophages, and B cells. These molecules play a crucial role in the immune response by presenting antigens to T cells, which then activate and differentiate into effector cells. The PE Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114] specifically recognizes the I-A and I-E alleles of the MHC class II molecules, which are expressed on different subsets of APCs. This allows for precise identification and characterization of these cells in various tissues and organs.

The PE Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114] is a valuable tool for researchers studying the immune system and its role in various diseases and conditions. Its high specificity and sensitivity make it ideal for detecting and quantifying MHC class II-expressing cells in complex biological samples. Additionally, the PE conjugation allows for easy multiplexing with other fluorescently labeled antibodies, enabling researchers to simultaneously analyze multiple cell populations and markers. Overall, the M5/114 antibody is a reliable and versatile reagent that can enhance the accuracy and efficiency of many immunological assays.