Neurocalcin Delta Polyclonal Antibody

Ab type

Primary antibody

Background

NCALD (neurocalcin delta) encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of NCALD have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from Neurocalcin δ . at AA range: 370-450

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

22245

synonyms

NCALD; Neurocalcin-delta