Neurexin IIIBeta Polyclonal Antibody

Ab type

Primary antibody

Background

NRXN3 (neurexin 3) encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from Neurexin IIIβ . at AA range: 30-110

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

69406

synonyms

NRXN3; KIAA0743; Neurexin-3-beta; Neurexin III-beta