Neuregulin-2 Polyclonal Antibody

Ab type

Primary antibody

Background

NRG2 encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human NRG2. AA range:361-410

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

91679

synonyms

NRG2; NTAK; Pro-neuregulin-2, membrane-bound isoform; Pro-NRG2