Neuregulin-1 SMDF Polyclonal Antibody

Ab type

Primary antibody

Background

The neuregulin 1 encoded by NRG1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human NRG1 isoform-10. AA range:1-50

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

31686

synonyms

Pro-neuregulin-1 membrane-bound isoform; Pro-NRG1; NRG1; GGF; HGL; HRGA; NDF; SMDF