Nesprin-3 Polyclonal Antibody

Ab type

Primary antibody

Background

Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human C14orf49. AA range:169-218

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

112216

synonyms

SYNE3; C14orf49; Nesprin-3; Nuclear envelope spectrin repeat protein 3