NES Monoclonal Antibody

Size

100ul

Clone Number

2C2F7

Aliases

Nestin, NES, Nbla00170

Immunogen Species

Human

UniProt ID

P48681

Immunogen

Recombinant Human Nestin protein

Raised in

Mouse

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, IF, FC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:500, IF:1:50-1:200

Background

Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.

Clonality

Monoclonal

Isotype

IgG1

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

NES

Research Areas

Neuroscience; Cancer; Cardiovascular; Developmental biology; Stem cells