NES Antibody

Size

100ug

Clone Number

Aliases

ESTM 46 antibody; FLJ 21841 antibody; FLJ21841 antibody; Intermediate filament protein antibody; Nbla00170 antibody; nes antibody; NEST_HUMAN antibody; Nestin antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P48681

Immunogen

Recombinant Human Nestin protein (1321-1569AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

NES

Research Areas

Neuroscience; Cancer; Cardiovascular; Developmental biology; Stem cells