NENF Antibody

Size

100ul

Clone Number

Aliases

Cell growth inhibiting protein 47 antibody; Cell immortalization-related protein 2 antibody; CIR2 antibody; Nenf antibody; NENF_HUMAN antibody; Neudesin antibody; Neuron derived neurotrophic factor antibody; Neuron-derived neurotrophic factor antibody; SCIRP10 antibody; SCIRP10 related protein antibody; Secreted protein of unknown function antibody; Spinal cord injury related protein 10 antibody; SPUF antibody; SPUF protein antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UMX5

Immunogen

Peptide sequence from Human Neudesin protein (149-167AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocyte. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (By similarity). Plays a role in the human tumorigenesis (PubMed:22748190).

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

NENF

Research Areas

Neuroscience; Tags & Cell Markers