NEK3 Antibody

Size

100ul

Clone Number

Aliases

NEK3 antibody; Serine/threonine-protein kinase Nek3 antibody; EC 2.7.11.1 antibody; HSPK 36 antibody; Never in mitosis A-related kinase 3 antibody; NimA-related protein kinase 3 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P51956

Immunogen

Recombinant Human Serine/threonine-protein kinase Nek3 protein (267-506AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin-mediated phosphorylation of PXN and VAV2. Implicated in prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

NEK3

Research Areas

Cancer; Signal transduction