NEDD4 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and| a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors| endocytic machinery components and the tumor suppressor PTEN.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human NEDD4

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

145090

synonyms

NEDD4