NDE1 Antibody

Size

100ul

Clone Number

Aliases

FLJ20101 antibody; HOM TES 87 antibody; LIS1 interacting protein NUDE1 rat homolog antibody; LIS1 interacting protein NUDE1 antibody; LIS4 antibody; NDE 1 antibody; NDE1 antibody; NDE1_HUMAN antibody; Nuclear distribution gene E homolog 1 antibody; Nuclear distribution protein nudE homolog 1 antibody; NUDE 1 antibody; NudE antibody; NudE nuclear distribution gene E homolog 1 (A. nidulans) antibody; NudE nuclear distribution gene E homolog 1 antibody; NUDE1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NXR1

Immunogen

Recombinant Human Nuclear distribution protein nudE homolog 1 protein (1-110AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Required for centrosome duplication and formation and function of the mitotic spindle. Essential for the development of the cerebral cortex. May regulate the production of neurons by controlling the orientation of the mitotic spindle during division of cortical neuronal progenitors of the proliferative ventricular zone of the brain. Orientation of the division plane perpendicular to the layers of the cortex gives rise to two proliferative neuronal progenitors whereas parallel orientation of the division plane yields one proliferative neuronal progenitor and a post-mitotic neuron. A premature shift towards a neuronal fate within the progenitor population may result in an overall reduction in the final number of neurons and an increase in the number of neurons in the deeper layers of the cortex.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

NDE1

Research Areas

Epigenetics and Nuclear Signaling; Neuroscience; Cell biology