NCOA6 Antibody

Size

100ug

Clone Number

Aliases

NCOA6 antibody; AIB3 antibody; KIAA0181 antibody; RAP250 antibody; TRBP antibody; Nuclear receptor coactivator 6 antibody; Activating signal cointegrator 2 antibody; ASC-2 antibody; Amplified in breast cancer protein 3 antibody; Cancer-amplified transcriptional coactivator ASC-2 antibody; Nuclear receptor coactivator RAP250 antibody; NRC RAP250 antibody; Nuclear receptor-activating protein antibody; 250 kDa antibody; Peroxisome proliferator-activated receptor-interacting protein antibody; PPAR-interacting protein antibody; PRIP antibody; Thyroid hormone receptor-binding protein antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q14686

Immunogen

Recombinant Human Nuclear receptor coactivator 6 protein (285-504AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

NCOA6

Research Areas

Others