NCOA5 Antibody

Size

100ug

Clone Number

Aliases

NCOA5 antibody; KIAA1637 antibody; Nuclear receptor coactivator 5 antibody; NCoA-5 antibody; Coactivator independent of AF-2 antibody; CIA antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9HCD5

Immunogen

Recombinant Human Nuclear receptor coactivator 5 protein (112-283AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IF; Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200

Background

Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC in response to 17-beta-estradiol (E2).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

NCOA5

Research Areas

Epigenetics and Nuclear Signaling