NCF1C Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

The neutrophil cytosolic factor 1 (NCF1) gene encodes the 47 kDa cytosolic subunit of neutrophil NADPH oxidase| which produces superoxide anion. The NCF1 gene is located in close proximity to two highly similar| multi-exon pseudogenes at chromosome 7q11.23| corresponding to this gene record and GeneID:654816. The two pseudogenes contain a dinucleotide deletion (delta-GT) in exon 2 that results in a frameshift and truncation of the open reading frame| and neither pseudogene is likely to express a protein. Recombination events between the pseudogenes and the functional NCF1 gene can inactivate the NCF1 gene and result in chronic granulomatous disease.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human NCF1C

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

40260

synonyms

NCF1C