NCAM1 Monoclonal Antibody,PE Conjugated

Size

Clone Number

Aliases

Immunogen Species

Human

UniProt ID

P13591

Immunogen

Recombinant Protein

Raised in

Mouse

Species Reactivity

Human

Tested Applications

ELISA,IF,FC;Recommended dilution:IF:1:100-1:200

Background

COC56 reacts with CD56, a 175-220 kDa Neural Cell Adhesion Molecule (NCAM), expressed on 10-25% of peripheral blood lymphocytes, including all CD16+ NK cells and approximately 5% of CD3+ lymphocytes, referred to as NKT cells. It also is present at brain and neuromuscular junctions, certain LGL leukemias, small cell lung carcinomas, neuronally derived tumors, myeloma and myeloid leukemias. CD56 (NCAM) is involved in neuronal homotypic cell adhesion which is implicated in neural development, and in cell differentiation during embryogenesis.1. Knapp, W et al., eds. (1989) Leucocyte Typing  IV: White Cell Differentiation Antigens, Oxford University Press, New York.2. Lanier LL . et al. (1991)  J. Immunol. 146:4421-4426.3. Campbell, JJ et al. (2001) J. Immunol . 166:6477-6482.4. Cooper MD  et al. (2001)  Trends in Immunol. 22:633-640.5. Galandrini R  et al. (2002)  Blood. 100:4581-4589.

Clonality

Monoclonal

Isotype

IgG1

Purification Method

Affinity purified

Conjugate

Non-conjugated

Buffer

Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA

Form

liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

NCAM1

Research Areas

Neuroscience;Signal transduction?Stem cells