NBK(Phospho Thr33) Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human BIK around the phosphorylation site of Thr33. AA range:18-67

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

18016

synonyms

Bcl-2-interacting killer; BIK; NBK; Bcl-2-interacting killer; Apoptosis inducer NBK; BIP1; BP4