NAL12 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein| which contains an N-terminal pyrin domain| a NACHT domain| a NACHT-associated domain| and a C-terminus leucine-rich repeat region| functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human NAL12

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

116710

synonyms

NAL12