NACAD Polyclonal Antibody

Ab type

Primary antibody

Background

May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites).

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human NACAD. AA range:376-425

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

161117

synonyms

NACAD; KIAA0363; NAC-alpha domain-containing protein 1