Na+/K+-ATPase alpha 1 Polyclonal Antibody

Ab type

Primary antibody

Background

The ATPase Na+/K+ transporting subunit alpha 1 encoded by ATP1A1 belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.

Reactivity

Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from rat ATP1 alpha1/Na+K+ ATPase1. AA range:15-64

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

113054

synonyms

Sodium/potassium-transporting ATPase subunit alpha-1; ATP1A1; Sodium/potassium-transporting ATPase subunit alpha-1; Na;+/K;+ ATPase alpha-1 subunit; Sodium pump subunit alpha-1