N4BP2 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region| and a Small MutS Related (Smr) domain near the C-terminal region. The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural precursor cell expressed| developmentally downregulated 4| (Nedd4) proteins. This protein binds and hydrolyzes ATP| may function as a 5'-polynucleotide kinase| and has the capacity to be a ubiquitylation substrate. This protein may play a role in transcription-coupled DNA repair or genetic recombination. Alternative splicing results in multiple transcript variants encoding different isoforms.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human N4BP2

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

194700

synonyms

N4BP2