Myosin VI Polyclonal Antibody

Ab type

Primary antibody

Background

MYO6 encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The unconventional myosin-VI consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from Myosin VI . at AA range: 40-120

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

149691

synonyms

MYO6; KIAA0389; Unconventional myosin-VI; Unconventional myosin-6