Myomesin-2 Polyclonal Antibody

Ab type

Primary antibody

Background

The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. Myomesin-2 contains 1,465 amino acids. Like MYOM1, Myomesin-2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that Myomesin-2 and bovine M protein are identical.

Reactivity

Human;Mouse;Monkey

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human MYOM2. AA range:612-661

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

164794

synonyms

MYOM2; Myomesin-2; 165 kDa connectin-associated protein; 165 kDa titin-associated protein; M-protein; Myomesin family member 2