MYOF Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

Mutations in dysferlin| a protein associated with the plasma membrane| can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events| suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected| but their full-length nature has not been determined.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human MYOF

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

226710

synonyms

MYOF