MYO1E Antibody

Size

100ug

Clone Number

Aliases

FSGS6 antibody; HuncM-IC antibody; MYO1C antibody; Myo1e antibody; MYO1E variant protein antibody; MYO1E_HUMAN antibody; Myosin heavy chain myr 3 antibody; Myosin IC, formerly antibody; Myosin IE antibody; Myosin-Ic antibody; Myr 3 antibody; Myr3 antibody; MYR5 antibody; Unconventional myosin 1E antibody; Unconventional myosin Ie antibody; Unconventional myosin-Ie antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q12965

Immunogen

Recombinant Human Unconventional myosin-Ie protein (62-189AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:500-1:1000

Background

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain. Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via ARL14EP and ARL14.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MYO1E

Research Areas

Signal transduction