MYO1C Antibody

Size

100ul

Clone Number

Aliases

MMI beta antibody; MMI-beta antibody; MMIb antibody; MYO1C antibody; MYO1C_HUMAN antibody; Myosin I beta antibody; Myosin Ic antibody; Myosin-Ic antibody; MYR2 antibody; NMI antibody; Nuclear myosin I antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O00159

Immunogen

Recombinant Human Unconventional myosin-Ic protein (804-1063AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane. Component of the hair cell\\\'s (the sensory cells of the inner ear) adaptation-motor complex. Acts as a mediator of adaptation of mechanoelectrical transduction in stereocilia of vestibular hair cells. Binds phosphoinositides and links the actin cytoskeleton to cellular membranes.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MYO1C

Research Areas

Signal transduction