MyD88 Polyclonal Antibody

Ab type

Primary antibody

Background

MyD88 encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. Myeloid differentiation primary response protein MyD88 functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human MyD88. AA range:171-220

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

33233

synonyms

MYD88; Myeloid differentiation primary response protein MyD88