MX2 Antibody

Size

100ug

Clone Number

Aliases

Interferon induced GTP binding protein Mx2 antibody; Interferon regulated resistance GTP binding protein MXB antibody; Interferon-induced GTP-binding protein Mx2 antibody; Interferon-regulated resistance GTP-binding protein MxB antibody; MX 2 antibody; MX dynamin like GTPase 2 antibody; Mx2 antibody; MX2_HUMAN antibody; MXB antibody; Myxovirus (influenza virus) resistance 2 antibody; Myxovirus resistance 2 antibody; Myxovirus resistance protein 2 antibody; p78 related protein antibody; p78-related protein antibody; Second interferon induced protein p78 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P20592

Immunogen

Recombinant Human Interferon-induced GTP-binding protein Mx2 protein (548-688AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

Background

Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the subsequent chromosomal integration of the proviral DNA. Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle progression.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MX2

Research Areas

Immunology