MX1 Antibody

Size

100ug

Clone Number

Aliases

Human interferon regulated resistance GTP binding protein MXA antibody; IFI 78 antibody; IFI 78K antibody; IFI-78K antibody; IFI78 antibody; IFI78K antibody; Interferon induced GTP binding protein Mx1 antibody; Interferon induced protein p78 antibody; Interferon inducible protein p78 antibody; Interferon regulated resistance GTP binding protein antibody; Interferon regulated resistance GTP binding protein MxA antibody; Interferon-induced GTP-binding protein Mx1 antibody; Interferon-induced protein p78 antibody; Interferon-regulated resistance GTP-binding protein MxA antibody; MX 1 antibody; MX antibody; MX dynamin-like GTPase 1 antibody; MX1 antibody; MX1_HUMAN antibody; MxA antibody; Myxoma resistance protein 1 antibody; Myxovirus (influenza virus) resistance 1 interferon inducible antibody; Myxovirus (influenza virus) resistance 1 interferon inducible protein p78 antibody; Myxovirus (influenza) resistance 1 homolog of murine antibody; Myxovirus resistance 1; mouse; homolog of antibody; Myxovirus resistance protein 1 antibody; N-terminally processed antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P20591

Immunogen

Recombinant Human Interferon-induced GTP-binding protein Mx1 protein (7-172AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC, IF, IP; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200, IP:1:200-1:2000

Background

Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MX1

Research Areas

Immunology; Microbiology