MUS81 Antibody

Size

100ug

Clone Number

Aliases

Crossover junction endonuclease MUS81 antibody; FLJ21012 antibody; FLJ44872 antibody; Mus 81 antibody; MUS81 antibody; MUS81 Endonuclease Homolog antibody; MUS81_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q96NY9

Immunogen

Recombinant Human Crossover junction endonuclease MUS81 protein (82-265AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

Background

Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5\\\'-end at the branch nick. Typical substrates include 3\\\'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MUS81

Research Areas

Epigenetics and Nuclear Signaling; Cancer