MUC20 Antibody

Size

100ug

Clone Number

Aliases

MUC 20 antibody; MUC-20 antibody; Muc20 antibody; MUC20_HUMAN antibody; Mucin 20 antibody; Mucin 20, cell surface associated antibody; Mucin-20 antibody; Transmembrane mucin MUC20S antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q8N307

Immunogen

Recombinant Human Mucin-20 protein (569-657AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:200-1:500

Background

May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MUC20

Research Areas

Signal transduction