MTU1 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This nuclear gene encodes a mitochondrial tRNA-modifying enzyme. The encoded protein catalyzes the 2-thiolation of uridine on the wobble positions of tRNA(Lys)| tRNA(Glu)| and tRNA(Gln)| resulting in the formation of 5-taurinomethyl-2-thiouridine moieties. Mutations in this gene may cause transient infantile liver failure. Polymorphisms in this gene may also influence the severity of deafness caused by mitochondrial 12S ribosomal RNA mutations. Alternative splicing results in multiple transcript variants.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human MTU1

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

46310

synonyms

MTU1