MTCH2 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus| which is highly expressed in white adipose tissue and adipocytes| and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target| and that its mRNA can give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human MTCH2

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

33330

synonyms

MTCH2