MSX2 Antibody

Size

100ug

Clone Number

Aliases

CRS 2 antibody; CRS2 antibody; FPP antibody; Homeo box msh like 2 antibody; Homeobox protein Hox-8 antibody; Homeobox protein MSX 2 antibody; Homeobox protein MSX-2 antibody; Homeobox protein MSX2 antibody; Hox 8 antibody; Hox8 antibody; MSH antibody; Msh homeo box 2 antibody; Msh homeo box homolog antibody; Msh homeo box homolog 2 antibody; Msh homeobox 2 antibody; Msh homeobox homolog 2 antibody; Msx 2 antibody; MSX2 antibody; MSX2_HUMAN antibody; Parietal foramina 1 antibody; PFM 1 antibody; PFM antibody; PFM1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P35548

Immunogen

Recombinant Human Homeobox protein MSX-2 protein (50-120AA)

Raised in

Rabbit

Species Reactivity

Human, Rat

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200

Background

Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antogonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MSX2

Research Areas

Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Cardiovascular; Signal transduction