Msx-2 Polyclonal Antibody

Ab type

Primary antibody

Background

MSX2 encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in MSX2 are associated with parietal foramina 1 and craniosynostosis type 2.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human Msx-2.

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

28867

synonyms

MSX2; HOX8; Homeobox protein MSX-2; Homeobox protein Hox-8