MSRB1 Antibody

Size

100ug

Clone Number

Aliases

Annexin A2 like antibody; EC 1 8 4 antibody; HSPC 270 antibody; HSPC270 antibody; Methionine R sulfoxide reductase antibody; Methionine R sulfoxide reductase B1 antibody; Methionine sulfoxide reductase antibody; Methionine-R-sulfoxide reductase B1 antibody; MGC3344 antibody; MSRB 1 antibody; MsrB1 antibody; MSRB1_HUMAN antibody; OTTHUMP00000159418 antibody; Sel X antibody; Selenoprotein R antibody; Selenoprotein X 1 antibody; Selenoprotein X antibody; Selenoprotein X1 antibody; SELR antibody; SelX antibody; SEPX 1 antibody; sepx1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NZV6

Immunogen

Recombinant Human Methionine-R-sulfoxide reductase B1 protein (1-116AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MSRB1

Research Areas

Cancer; Cell biology; Metabolism; Signal transduction