MSH2 Polyclonal Antibody

Ab type

Primary antibody

Background

MSH2 is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E.coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human MSH2. AA range:541-590

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

104743

synonyms

MSH2; DNA mismatch repair protein Msh2; hMSH2; MutS protein homolog 2