MS4A2 Antibody

Size

100ug

Clone Number

Aliases

APY antibody; ATOPY antibody; Fc epsilon receptor I beta-chain antibody; Fc IgE receptor beta chain antibody; FCER1B antibody; FCERB_HUMAN antibody; FcERI antibody; High affinity immunoglobulin epsilon receptor subunit beta antibody; IgE Fc receptor subunit beta antibody; IGEL antibody; IGHER antibody; Membrane-spanning 4-domains subfamily A member 2 antibody; MS4A1 antibody; Ms4a2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q01362

Immunogen

Recombinant Human High affinity immunoglobulin epsilon receptor subunit beta protein (1-59AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

Background

High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

MS4A2

Research Areas

Others