MRP-S5 Polyclonal Antibody

Ab type

Primary antibody

Background

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPS5 (mitochondrial ribosomal protein S5) encodes a 28S subunit protein that belongs to the ribosomal protein S5P family. Pseudogenes corresponding to MRPS5 are found on chromosomes 4q, 5q, and 18q.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human MRPS5. AA range:367-416

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

48006

synonyms

MRPS5; 28S ribosomal protein S5; mitochondrial; MRP-S5; S5mt