MRP-S32 Polyclonal Antibody

Ab type

Primary antibody

Background

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL42 encodes mitochondrial ribosomal protein L42 identified as belonging to both the 28S and the 39S subunits. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human MRPS42. AA range:75-124

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

16661

synonyms

MRPL42; MRPL31; MRPS32; RPML31; HSPC204; PTD007; 39S ribosomal protein L42; mitochondrial; L42mt; MRP-L42; 28S ribosomal protein S32, mitochondrial; MRP-S32; S32mt; 39S ribosomal protein L31, mitocho